Endocrine Abstracts

Polycystic ovary syndrome (PCOS) is characterized by laboratory and/or clinical features consisting of hyperandrogenism with chronic anovulation. and is currently one of the most common endocrinopaties in women of fertile age. PCOS is associated with a variety of endocrine and metabolic disturbances. It is well known that women are more prone to develop autoimmune diseases compared to men and levels of sexual hormones are thought to be responsible for such a difference. Our ai...

Background: GnRH is the first key hormone of reproduction. GnRH analogs are extensively used in IVF, and treatment of sex hormone-dependent cancers due to ability to bring about ‘chemical castration’. Recent studies have demonstrated that GnRH and sex steroids exert not only hormonal effects but play an important role in the immune system modulation.Case report: We report a case of vasculitis and severe polymyositis developed 5 days after GnRH ...